Parental typediabetes can affect children's cognitive development
Date:
April 26, 2022
Source:
PLOS
Summary:
Cognitive development in children could be affected regardless of
which biological parent has type 1 diabetes, according to a new
study. The research shows for the first time that having a parent
with a chronic disease like type 1 diabetes may be associated with
lower school performance rather than maternal high blood sugar
during fetal development.
FULL STORY ========================================================================== Cognitive development in children could be affected regardless of which biological parent has type 1 diabetes, according to research publishing
April 19 in the open access journal PLOS Medicine.The research shows
for the first time that having a parent with a chronic disease like type
1 diabetes may be associated with lower school performance rather than
maternal high blood sugar during fetal development.
==========================================================================
The influence of maternal diabetes during pregnancy on the cognition of
their children has been widely researched. Glucose crosses the placenta
and maternal high blood sugar, hyperglycemia, can affect fetal development including the baby's brain. There is little evidence on different diabetes subtypes and the effect of having a father with type 1 diabetes.
Anne Laerke Spangmose and colleagues from Copenhagen University Hospital, Denmark obtained data from Danish registers and also on test scores in
math for grades three and six, and reading for grades two, four, six and
eight. The team included 622,073 children between 6-18 years old attending public schools over a seven-year period. There were 2,144 children with
mothers with type 1 diabetes, 3,474 children with fathers with type 1
diabetes, and 616,455 children from the background population. Children
of mothers and fathers with type 1 diabetes had mean scores of 54.2 and
54.4 respectively, compared with mean scores of 56.4 in children from
the background population.
The team acknowledge that having a parent suffering from a serious
chronic disease like diabetes could cause stress and be detrimental to
a child's school performance. However this study suggests a different explanation for previously observed adverse effects of maternal type 1
diabetes during pregnancy on children's cognitive development.
Spangmose adds, "Lower test scores in the offspring of mothers with type
1 diabetes appear to reflect a negative association of having a parent
with type 1 diabetes rather than a specific adverse effect of maternal
type 1 diabetes during pregnancy on the fetus. Our recent large Danish
cohort study, including 622,073 children, has shown this."
========================================================================== Story Source: Materials provided by PLOS. Note: Content may be edited
for style and length.
========================================================================== Journal Reference:
1. Anne Laerke Spangmose, Niels Skipper, Sine Knorr, Tina Wullum
Gundersen,
Rikke Beck Jensen, Peter Damm, Erik Lykke Mortensen, Anja
Pinborg, Jannet Svensson, Tine Clausen. School performance in
Danish children exposed to maternal type 1 diabetes in utero:
A nationwide retrospective cohort study. PLOS Medicine, 2022; 19
(4): e1003977 DOI: 10.1371/ journal.pmed.1003977 ==========================================================================
Link to news story:
https://www.sciencedaily.com/releases/2022/04/220426153616.htm
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